Tuberculosis and diabetes: the deadly duo

Deadly duo

An astonishing one-third of the world’s population is infected with the bacterium that causes tuberculosis (TB), Mycobacterium tuberculosis. In most people it remains inactive or latent but in about 10% of people an active case of TB disease will develop within their lifetime. Simple antibiotics can prevent and treat most of these cases, yet 8-10 million people develop an active TB infection an...

HIV & TB “ The Deadly Duo ”

WHO estimates that more than 7 million people, 98% of whom are in the developing world are co-infected with HIV and TB. The situation is explosive, leading to unprecedented public health crises. Both diseases are devastating but the devastation of the TB /HIV co-epidemic surpasses the devastation of either disease on its own. An estimated 1.4 million new cases of HIV-TB occurred in 2008, repres...

Diabetes and Critical Limb Ischemia: The Deadly Duo in Patients with Symptomatic Peripheral Artery Disease.

Inflammation plays an important role in the initiation and progression of peripheral artery disease (PAD). Patients with diabetes have an increased risk of developing PAD. Data regarding the prognostic implication of diabetes and inflammation on all-cause mortality in patients with symptomatic PAD and preserved left ventricular ejection fraction (LVEF >50%). The study was conducted at the Sestr...

HIV and tuberculosis--a "cursed duo" in the HAART era.

HIV and tuberculosis: a deadly human syndemic.

A syndemic is defined as the convergence of two or more diseases that act synergistically to magnify the burden of disease. The intersection and syndemic interaction between the human immunodeficiency virus (HIV) and tuberculosis (TB) epidemics have had deadly consequences around the world. Without adequate control of the TB-HIV syndemic, the long-term TB elimination target set for 2050 will no...